Coya completes of Phase 2 study of LD IL-2 to treat moderate AD

Coya Therapeutics announces the completion of a randomized, double-blind, placebo-controlled Phase 2 study of LD IL-2 in patients with mild-to-moderate AD. The study is being conducted by Drs. Stanley Appel and Alireza Faridar at Houston Methodist Hospital and is funded by the Gates Foundation and the Alzheimer’s Association. Topline results of the study are still anticipated to be reported in summer of 2024. This controlled Phase 2 study will evaluate the safety, tolerability, and biological activity of LD IL-2 in patients with AD compared to placebo at pre-specified intervals. Additionally, blood and cerebrospinal fluid biomarkers, neuroimaging results, and changes in cognitive function will be evaluated across the different patient populations. Fred Grossman D.O., President and CMO of Coya Therapeutics, stated, “This is an important study that will help advance our expanding pipeline in dementia. We look forward to unblinding the data from this controlled study in Alzheimer’s Disease and releasing the top-line results this summer…