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Coherus Biosciences announces clinical collaboration with CRI

Coherus BioSciences announced that the Cancer Research Institute, CRI, and its Immunotherapy Platform Study in Platinum-Resistant High-Grade Serous Ovarian Cancer, IPROC, Drug Selection Committee, DSC, have selected LOQTORZI, anti-PD-1 antibody, to explore in combination with ENB-003, a first-in-class small molecule inhibitor of endothelin B receptor, for the treatment of drug-resistant cancers in the iPROC platform study. Endothelin B receptor is implicated in tumorigenesis and tumor immune suppression for several solid tumors, including melanoma, ovarian, and pancreatic cancers.

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