Charles River in collaboration with MatTek awarded $1.3M grant from FCRI

Charles River Laboratories International announced a multidisciplinary program, funded through a $1.3M grant from the Foundation for Chemistry Research & Initiatives FCRI, in coordination with the American Chemistry Council’s Long-Range Research Initiativ ACC LRI , to develop a New Approach Methodology NAM inhalation toxicology test to reduce reliance on traditional animal research methods. The program is a collaboration between Charles River’s Edinburgh, Scotland team, along with MatTek Corporation (in vitro EpiAirway model and expertise), dosimetry modeling by Battelle, and modeling consultancy from Greek Creek Toxicokinetics Consulting, . This collaboration is guided by Charles River’s Alternative Methods Advancement Project an initiative focused on reducing the use of animals in research. “We are deeply committed to advancing alternative methods, and this program is an important step toward removing the need for animal models in inhalation toxicology studies,” said Shannon Parisotto, Corporate Executive Vice President, Global Discovery & Safety Assessment. “Charles River’s industry-leading expertise uniquely positions us to progress research in this area, and we are excited by the multidisciplinary