Cellares, Cabaletta Bio team to evaluate CABA-201 manufacturing on Cell Shuttle

Cellares, the first Integrated Development and Manufacturing Organization IDMO dedicated to clinical and industrial-scale cell therapy manufacturing, and Cabaletta Bio, announced Cabaletta will evaluate Cellares’ automated manufacturing platform, the Cell Shuttle, through Cellares’ Technology Adoption Partnership TAP program. As part of the collaboration, the companies have agreed on a proof-of-concept technology transfer process for the manufacture of CABA-201, Cabaletta’s clinical-stage fully human CD19-CAR T cell product candidate, using the Cell Shuttle. manufacturing in order to meet the potential demand from patients,” said Gwendolyn Binder, Ph.D., President of Science and Technology at Cabaletta. “Cellares has made impressive progress with their automated cell therapy manufacturing capabilities. Their dedication to deploying these technologies at scale aligns well with our goal of bringing potentially transformative therapies to patients with autoimmune diseases.” “This partnership enables us to leverage the unique capabilities of our Cell Shuttle platform to accelerate the production of CABA-201, Cabaletta Bio’s innovative CD19-CAR T product candidate,” said Fabian Gerlinghaus, CEO of Cellares. “Through our Technology Adoption Partnership program, we aim to fully automate all cell therapy manufacturing processes, thereby bringing us a step closer to potentially delivering CAR T cell therapies for patients with a broad range of autoimmune diseases. Together, we’re not just enhancing manufacturing efficiency, but also fostering an environment that can facilitate the rapid advancement of life-altering therapies.”