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C4 Therapeutics announces FDA cleared IND application for CFT8919

C4 Therapeutics, or C4T, announced that the FDA has cleared the company’s investigational new drug, or IND, application for CFT8919, an orally bioavailable BiDAC degrader designed to be potent and selective against EGFR L858R for non-small cell lung cancer, or NSCLC, patients. This milestone marks C4T’s fourth IND clearance from its proprietary TORPEDO platform. In May 2023, C4T and Betta Pharmaceuticals entered into an exclusive licensing agreement for the development and commercialization of CFT8919 in Greater China, including Hong Kong SAR, Macau SAR and Taiwan.

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