Bullfrog AI issued U.S. patent for novel prodrugs of mebendazole

BullFrog AI Holdings announced that the United States Patent and Trademark Office will, on August 1, 2023, issue U.S. Patent No. 11,712,435 protecting the Company’s novel prodrugs derived from mebendazole and their use in treating cancers and other diseases. The patented compounds exhibit improved solubility and oral bioavailability relative to the parent drug, thereby addressing a key difficulty encountered in evaluating the potential use of mebendazole for oncology indications.U.S. Patent No. 11,712,435 represents the first issued patent resulting from intellectual property BullFrog AI licensed from Johns Hopkins University in October 2022. BullFrog AI’s exclusive, worldwide, royalty-bearing license includes the rights to commercialize prodrugs of mebendazole that demonstrate improved solubility and bioavailability relative to the parent compound.