After BridgeBio (BBIO) reported “positive” data from the phase 3 ATTRibute-CM trial evaluating acoramidis in ATTR-CM, or transthyretin amyloidosis cardiomyopathy, BofA said the data that exceeded expectations and showed benefit in all-cause mortality read through positively to Alnylam (ALNY) and “bodes well” for the HELIOS-B readout of vutrisiran in ATTR-CM due in early 2024. The firm, which said BridgeBio’s results reinforce its confidence in vutrisiran’s commercial opportunity in ATTR-CM, maintains a Buy rating and $262 on Alnylam shares.
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