Aura Biosciences announced the presentation of positive interim Phase 2 safety and efficacy data of bel-sar with 9-10 months of follow up evaluating two key clinical endpoints: tumor control and visual acuity preservation using the suprachoroidal route of administration for the first-line treatment of patients with early-stage choroidal melanoma. The results were presented at the Macula Society 46th Annual Meeting held February 15-18, 2023, in Miami, FL. "The data presented today with an average of nine months of follow up for patients treated with three cycles of therapy, show an excellent response to the therapy with 89-100% tumor control. In addition, the safety profile to date has been favorable with only one patient losing visual acuity and no treatment-related SAEs or significant AEs, which is encouraging given that the majority of these patients had tumors close to the fovea or optic disk and would have likely experienced severe and irreversible vision loss with the current standard of care with radiotherapy," said Dr. Ivana Kim, Director of the Ocular Melanoma Center, Massachusetts Eye and Ear. "These latest results strongly support the potential of bel-sar to be used as a first line treatment option for patients with early-stage choroidal melanoma."
Published first on TheFly
