Atossa Therapeutics provides five-year Z-Endoxifen treatment update

Atossa Therapeutics announced that the pre-menopausal, Estrogen Receptor positive / Human Epidermal Growth Factor Receptor 2 negative, breast cancer patient who received neoadjuvant and adjuvant-endoxifen therapy under an FDA-approved “expanded access” program has completed five years of treatment. As of the date of this press release, the patient remains cancer-free and has reported no significant safety or tolerability issues over the course of her treatment. Atossa is a clinical stage biopharmaceutical company developing innovative medicines in areas of significant unmet medical need in oncology with a focus on breast cancer. “We believe this patient, and her successful treatment journey, is representative of the opportunity (Z)-endoxifen has to change the treatment paradigm for the approximately 250,000 women diagnosed with estrogen receptor positive breast cancer each year in the U.S.,” said Steven Quay, M.D., Ph.D., Atossa’s President and Chief Executive Officer. “The current standard of care is sub-optimal as it often requires ovarian suppression in premenopausal women and aromatase inhibitors in postmenopausal women, both of which are associated with potential short-term and long-term side effects that diminish adherence. Over five years of adjuvant treatment, her daily (Z)-endoxifen treatment has been well tolerated, and there were no vasomotor symptoms commonly associated with standard of care adjuvant pharmaceuticals. She remains cancer-free today and we are grateful to have been able to help her with a difficult treatment problem.”