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AstraZeneca signs exclusive option and global license agreement with Allorion

AstraZeneca has entered into an exclusive option and global license agreement with Allorion Therapeutics, a US and China-based biotechnology company that focuses on the discovery of new small molecule drugs for treating cancer and autoimmune diseases, to develop and commercialize a novel epidermal growth factor receptor – EGFR – L858R mutated allosteric inhibitor, as a potential new treatment for advanced EGFR-mutant non-small cell lung cancer or NSCLC. AstraZeneca will be granted an exclusive option to license a novel EGFR L858R allosteric inhibitor to develop and commercialize globally. Allorion is eligible to receive upfront and near-term payments of up to $40 million, and additional development and commercial milestone payments of over $500M, as well as tiered royalties on net sales worldwide.

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