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Assembly Biosciences provides anticipated development milestones for 2024
The Fly

Assembly Biosciences provides anticipated development milestones for 2024

Assembly Biosciences provided an outline of the anticipated milestones and progress for its clinical pipeline during 2024. By mid-year 2024: ABI-5366, a long-acting herpes simplex virus helicase-primase inhibitor targeting recurrent genital herpes, is expected to enter a first-in-human clinical study; and ABI-4334, a highly potent next-generation capsid assembly modulator, is anticipated to enter a Phase 1b study in chronic hepatitis B virus patients. By the end of 2024: Two additional candidates are anticipated to enter the clinic: ABI-1179, the long-acting HSV helicase-primase inhibitor contributed by Gilead under the collaboration between Assembly Bio and Gilead; and ABI-6250, a small molecule orally-bioavailable hepatitis delta virus entry inhibitor. Initial clinical data are expected to be available from both the ABI-5366 first-in-human clinical study and the ABI-4334 Phase 1b study.

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