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Arvinas upgraded to Buy at Jefferies after vepdegestrant combo data reported

As previously reported, Jefferies upgraded Arvinas (ARVN) to Buy from Hold with a price target of $40, up from $32, after the company and Pfizer (PFE) announced clinical data for vepdegestrant in combination with palbociclib. The firm thinks the combo looks “competitive” and potentially differentiated from peers and believes Pfizer and Arvinas are running “smart trials,” the analyst tells investors. While it is still not fully clear, the firm’s analysis suggests that efficacy is not driven by higher palbociclib exposure, the analyst added.

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