Apogee announces first patients dosed ahead of schedule in trial of APG777

Apogee Therapeutics announced that it has initiated dosing of healthy volunteers in its first clinical trial for APG777, its lead product candidate being developed as a frontline treatment for moderate-to-severe AD and other inflammatory diseases. Initiation of this trial marks a milestone for the company and its approach. “The initiation of this Phase 1 study of APG777 represents an important advancement for Apogee, now a clinical-stage organization, and for our discovery research collaboration with Paragon, a pioneer in developing best-in-class biologics for a range of diseases,” said Michael Henderson, M.D., Chief Executive Officer of Apogee. “By leveraging known targets with differentiated monoclonal antibodies, Apogee has the potential to improve the course of treatment for multiple inflammatory disorders, and APG777 is just the start of our strategy to develop a broad pipeline of potentially best-in-class product candidates. I am proud of the Apogee team’s rapid progress in advancing APG777 to this new stage, ahead of our initial timeline expectations.”