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Acelyrin down 62% to $10.55 after izokibep did not meet study endpoint

Shares of Acelyrin (SLRN) are down 62% or $17.35 at $10.55 after the company announced top-line results from Part B of a Phase 2b/3 trial evaluating izokibep for the treatment of moderate-to-severe Hidradenitis Suppurativa, or HS. The primary endpoint of HiSCR75 at week 16 did not meet statistical significance. Moonlake Therapeutics (MLTX), which is also developing a treatment for HS, is up 19% at $63.00 on the news.

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