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Acelyrin announces PoC data from Phase 1/2 trial of lonigutamab

ACELYRIN announced that data from its Phase 1/2 clinical trial of lonigutamab in thyroid eye disease will be shared in a rapid-fire oral presentation at the 42nd Annual Meeting of the European Society of Ophthalmic Plastic and Reconstructive Surgery taking place from September 12-14, 2024 in Rotterdam, Netherlands. “The rapid suppression of IGF-1 receptor signaling observed with lonigutamab could potentially improve clinical outcomes for patients by achieving robust clinical responses with low drug exposures,” said Shephard Mpofu, M.D., Chief Medical Officer of ACELYRIN. “Importantly, we believe these data are supportive of the potential for subcutaneously-delivered lonigutamab to provide deep and durable responses with convenient, self-administered dosing.”

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