ABVC BioPharma provides 2023 pipeline update

ABVC BioPharma provided an update to drug and medical device developments expected in 2023. Major Depressive Disorder: ABVC‘s MDD medicine, ABV-1504, has successfully completed Phase II at the Stanford University Medical Center and five major medical centers in Taiwan. Later this year, with the help of Dr. Maurizio Fava and Dr. Thomas Laughren, the company expects to conclude discussions with the US FDA on acceptable protocols for Phase III trials for MDD, allowing ABVC to seek potential distribution partners active in manufacturing and distributing Central Nervous System medicines. ADHD: The company’s ADHD medicine ABV-1505, is currently in Phase II, part 2, clinical trials at five prestigious medical centers in Taiwan. In addition, in the next several months the part 2 study will begin at the University of California, San Francisco Medical Center. This study is expected to eventually enroll approximately 100 patients in Taiwan and the United States. Cancer Patient Depression: A Phase I study of ABV-1601 for treating depression in cancer patients is expected to begin in the first Quarter of 2023 at the Cedars-Sinai Medical Center. The Phase I study is open label and will be conducted with 12 cancer patients with moderate to severe depressive symptoms. The main objective of the study is to evaluate the safety of PDC-1421, the primary active ingredient in ABV-1601 in cancer patients. Oncology: ABVC has initiated a Phase II trial for ABV-1703 for pancreatic cancer at the Cedars Sinai Medical Center utilizing an herbal active ingredient that showed significant promise during Phase I testing conducted in Japan and at the Memorial Sloan Kettering Cancer Center. While the company’s additional oncology medicines have yet to be determined, ABVC anticipates clinical studies for ABV-1519 for non-small cell lung cancer and ABV-1501 for triple negative breast cancer will be initiated in Q3 2023. The clinical study for ABV-1702 for myelodysplastic syndrome is expected to start in Q4 of 2023. Vitargus: Vitargus is the first biodegradable vitreous substitute to facilitate retina reattachment surgery. The company expects to complete the Phase II trial of Vitargus in Thailand, Australia and Taiwan by the end of 2023 which may lead to distribution agreements in Asia by the end of 2023.