William Blair analyst Myles Minter has maintained their bullish stance on VRTX stock, giving a Buy rating today.
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Myles Minter’s rating is based on Vertex Pharmaceuticals’ recent advancements in their kidney portfolio, particularly with the acquisition of Alpine Immune Sciences. This acquisition has brought povetacicept, a promising dual APRIL/BAFF b-cell modulator, into Vertex’s pipeline, which has been granted Breakthrough Therapy Designation (BTD) by the FDA for the treatment of IgA nephropathy (IgAN). The BTD is significant as it indicates that the FDA recognizes the potential of povetacicept to offer substantial improvements over existing treatments, and it allows for expedited development and review processes.
Furthermore, the ongoing Phase III RAINIER study of povetacicept is expected to provide pivotal data that could lead to an accelerated approval filing in the first half of 2026. This progress, combined with the FDA’s favorable view of B-cell modulators in addressing unmet needs in IgAN, positions Vertex well for future growth. These factors contribute to the positive outlook and justify the Buy rating given by Minter.
In another report released today, Leerink Partners also upgraded the stock to a Buy with a $456.00 price target.