TD Cowen analyst Tyler Van Buren has maintained their bullish stance on BCAX stock, giving a Buy rating on April 30.
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Tyler Van Buren has given his Buy rating due to a combination of factors that highlight the promising potential of Bicara Therapeutics Inc.’s lead candidate, ficera. The company’s ongoing clinical trials, particularly in HPV-positive head and neck squamous cell carcinoma (HNSCC), have shown encouraging results with a high objective response rate and impressive depth and durability of response. These results suggest a potential best-in-indication profile, which significantly reduces the risk of the ongoing Phase II/III trial.
Ficera’s innovative approach, targeting both EGFR and TGF-β at the tumor site, addresses key resistance mechanisms associated with EGFR resistance. This dual-action strategy not only enhances the efficacy by targeting tumor growth and adaptive resistance but also provides a safety advantage by localizing TGF-β inhibition to the tumor microenvironment. The management’s confidence in this approach, combined with the compelling clinical data, supports the Buy rating as it indicates a promising future for Bicara’s pipeline across multiple indications.
In another report released on April 30, Stifel Nicolaus also maintained a Buy rating on the stock with a $48.00 price target.