H.C. Wainwright analyst Matthew Caufield has reiterated their bullish stance on LENZ stock, giving a Buy rating today.
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Matthew Caufield has given his Buy rating due to a combination of factors surrounding LENZ Therapeutics’ innovative approach in the presbyopia treatment space. The company’s lead product, LNZ100, is a novel aceclidine-based eye drop designed to improve near vision without relying on pilocarpine, which has been associated with safety concerns in previous treatments. This new mechanism targets the iris sphincter muscle, offering a safer and more durable solution for presbyopia, a common condition affecting the aging population.
Furthermore, Caufield highlights the strategic pre-commercial planning and infrastructure development by LENZ Therapeutics, which is crucial as they approach the PDUFA date in August 2025. The successful completion of pivotal Phase 3 trials in China, in collaboration with Corxel Pharmaceuticals, further strengthens the case for LNZ100, demonstrating significant improvements in near vision without compromising distance vision. These developments, along with anticipated commercial clarity in the upcoming year, reinforce the Buy rating as the company positions itself to redefine the presbyopia treatment landscape.

