New insider activity at Personalis ( (PSNL) ) has taken place on November 5, 2025.
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President & CEO Christopher Hall recently sold 29,612 shares of Personalis stock, amounting to a total transaction value of $266,211.
Recent Updates on PSNL stock
Personalis recently held its Q3 earnings call, revealing both strategic successes and financial challenges. The company reported a significant 364% year-over-year growth in clinical test volumes, indicating strong clinical adoption and physician enthusiasm for its NeXT Personal test. However, Personalis faced a 44% revenue decline compared to the previous year, primarily due to biopharma volatility and the conclusion of significant trials like Moderna’s Phase III melanoma trial. Despite these challenges, the company maintains a strong financial position with $150.5 million in cash and no significant debt. Strategic partnerships, such as with Tempus, have exceeded expectations, and Personalis is making progress in reimbursement, with expectations of securing Medicare coverage decisions by year-end. Analyst Thomas Flaten of Lake Street raised the firm’s price target for Personalis, citing the company’s Q3 revenue exceeding expectations and emphasizing that future growth will be driven by reimbursement advancements, despite lowered 2025 revenue guidance due to macroeconomic headwinds in the biopharma sector.
Spark’s Take on PSNL Stock
According to Spark, TipRanks’ AI Analyst, PSNL is a Neutral.
Personalis’ overall stock score reflects significant financial challenges, with declining revenues and profitability issues being the most impactful factors. While technical indicators show some positive momentum, the valuation remains unattractive due to negative earnings. The company’s strategic focus on clinical adoption and partnerships provides some optimism, but financial improvements are crucial for a better outlook.
To see Spark’s full report on PSNL stock, click here.
More about Personalis
YTD Price Performance: 39.23%
Average Trading Volume: 1,089,977
Technical Sentiment Signal: Buy
Current Market Cap: $774.2M