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Santhera’s Earnings Call: Positive Outlook Amid Challenges

Santhera’s Earnings Call: Positive Outlook Amid Challenges

Santhera Pharmaceuticals Holding Ag ((CH:SANN)) has held its Q2 earnings call. Read on for the main highlights of the call.

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Santhera Pharmaceuticals Holding AG’s recent earnings call conveyed a generally positive sentiment, underscored by the robust market adoption of AGAMREE in Europe and the U.S., alongside a successful commercial rollout in China. Despite these achievements, the company also faced challenges, including a significant operating loss and the necessity for additional financing.

Strong AGAMREE Adoption in Key Markets

AGAMREE has made impressive strides in key markets, capturing approximately 40% market share among steroid-using DMD patients in Germany and Austria. Notably, Austria has surpassed a 50% market share, highlighting the drug’s strong acceptance and potential for continued growth in these regions.

U.S. Market Performance

In the U.S., Catalyst reported first-half 2025 sales of USD 49.4 million, positioning the company well to meet its full-year guidance of $100 million to $110 million. Achieving this target would trigger a $12.5 million milestone payment to Santhera, further bolstering the company’s financial outlook.

Successful Commercial Rollout in China

Sperogenix’s non-reimbursed commercial rollout in China has commenced with over 250 patients, marking a significant growth opportunity for Santhera. This expansion underscores the company’s strategic focus on tapping into the vast potential of the Chinese market.

Increased Revenue Guidance

Santhera has revised its revenue guidance for 2025 upwards, now expecting revenues to exceed CHF 65 million to CHF 70 million. This adjustment reflects the strong market performance and the company’s confidence in its growth trajectory.

Operating Loss

Despite the positive developments, Santhera reported an operating loss of CHF 35.4 million for the first half of the year. This highlights the ongoing financial challenges the company faces as it continues to invest in its growth initiatives.

Additional Financing Required

To address increased inventory needs and delayed cash flow breakeven, Santhera has secured an additional CHF 20 million in financing. This move is crucial for maintaining the company’s operational momentum and supporting its strategic objectives.

Forward-Looking Guidance

During the earnings call, CFO Catherine Isted provided key financial guidance, emphasizing the company’s new CHF 20 million financing, which extends their runway to cash flow breakeven by mid-2026. Santhera’s global sales have surpassed $100 million, with full-year revenues expected to exceed CHF 65-70 million. The company anticipates continued growth in China and is expanding its market presence in Europe and North America, aiming for a market size exceeding $600 million.

In summary, Santhera Pharmaceuticals Holding AG’s earnings call highlighted a positive outlook with strong market adoption of AGAMREE and increased revenue guidance. However, the company must navigate challenges such as a significant operating loss and the need for additional financing. These factors will be crucial as Santhera continues to pursue its growth strategy in key global markets.

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