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Kezar Life Sciences Faces FDA Challenges in Drug Program

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Kezar Life Sciences Faces FDA Challenges in Drug Program

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Kezar Life Sciences ( (KZR) ) has provided an update.

On October 16, 2025, Kezar Life Sciences announced a regulatory update regarding its zetomipzomib program for autoimmune hepatitis, revealing challenges in aligning with the FDA on a clinical trial. The FDA’s request for additional studies could delay zetomipzomib’s development by two years, impacting Kezar’s operations and strategic direction. The company is exploring strategic alternatives, including restructuring and workforce reduction, to maximize shareholder value. Additionally, Kezar extended its Rights Plan to protect the strategic review process, ensuring fair participation and informed decision-making by the Board.

The most recent analyst rating on (KZR) stock is a Hold with a $7.00 price target. To see the full list of analyst forecasts on Kezar Life Sciences stock, see the KZR Stock Forecast page.

Spark’s Take on KZR Stock

According to Spark, TipRanks’ AI Analyst, KZR is a Neutral.

Kezar Life Sciences faces significant challenges typical of early-stage biotech companies, with no revenue and ongoing losses. While the balance sheet shows stability, the company is reliant on external funding. Technical indicators suggest negative momentum, and the valuation metrics are unattractive due to negative earnings. The lack of earnings call and corporate events data further impacts the assessment.

To see Spark’s full report on KZR stock, click here.

More about Kezar Life Sciences

Kezar Life Sciences is a clinical-stage biopharmaceutical company focused on developing novel small molecule therapeutics for immune-mediated diseases. Their primary product, zetomipzomib, is a selective immunoproteasome inhibitor with potential applications in autoimmune hepatitis and other chronic immune-mediated diseases.

Average Trading Volume: 42,875

Technical Sentiment Signal: Sell

Current Market Cap: $31.49M

For a thorough assessment of KZR stock, go to TipRanks’ Stock Analysis page.

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