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CytomX Therapeutics Reports Q1 2025 Results and Progress

CytomX Therapeutics Inc. ( (CTMX) ) has released its Q1 earnings. Here is a breakdown of the information CytomX Therapeutics Inc. presented to its investors.

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CytomX Therapeutics Inc., a clinical-stage biopharmaceutical company, focuses on developing novel conditionally activated biologics for cancer treatment, leveraging its PROBODY therapeutic platform to create safer, more effective therapies.

In its first quarter of 2025, CytomX Therapeutics reported positive interim data from its ongoing Phase 1 study of the CX-2051 EpCAM Antibody Drug Conjugate in advanced colorectal cancer patients, alongside financial results and strategic updates.

The company highlighted key financial metrics, including a revenue increase to $50.9 million from $41.5 million year-over-year, driven by collaborations with Bristol Myers Squibb and Amgen. Operating expenses decreased slightly to $28.3 million, reflecting cost reductions and restructuring efforts. Additionally, CytomX’s cash position was reported at $79.9 million, extending its financial runway into the second quarter of 2026.

Strategically, CytomX is advancing its CX-2051 program with ongoing dose expansions and plans for a Phase 2 study in 2026. The company is also progressing with its CX-801 program in melanoma, aiming for combination therapy trials with KEYTRUDA in 2025. Collaborations with major industry players like Astellas and Moderna continue to bolster its research pipeline.

Looking ahead, CytomX remains focused on advancing its clinical programs and leveraging strategic partnerships to enhance its pipeline, with a commitment to addressing unmet needs in oncology through its innovative biologics platform.

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