Corvus Pharmaceuticals Inc. ((CRVS)) announced an update on their ongoing clinical study.
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Corvus Pharmaceuticals Inc. is conducting a Phase 1 clinical study titled ‘A Phase 1, Randomized, Blinded, Placebo-controlled, Dose Escalation and Expansion Study to Investigate the Safety, Tolerability, and Preliminary Efficacy of ITK Inhibitor Soquelitinib in Participants With Moderate to Severe Atopic Dermatitis.’ The study aims to evaluate the safety, tolerability, and initial effectiveness of Soquelitinib in treating moderate to severe atopic dermatitis, a condition with significant unmet medical needs.
The study tests Soquelitinib, an experimental drug administered in tablet form, designed to inhibit ITK, a protein potentially involved in the inflammatory process of atopic dermatitis. Participants receive either Soquelitinib or a placebo during the study’s dose escalation and expansion phases.
This interventional study is randomized and follows a sequential model, with a quadruple-blind design to ensure unbiased results. Its primary purpose is treatment-focused, aiming to establish a safe and effective dosage for future studies.
The study began on March 12, 2024, with primary completion expected in 2025. The latest update was submitted on July 18, 2025, indicating ongoing recruitment and progress in the study.
For investors, this study could impact Corvus Pharmaceuticals’ stock, as successful results may enhance the company’s market position in the dermatology sector. The ongoing development of Soquelitinib could also influence investor sentiment positively, especially if it shows promise compared to existing treatments.
The study is currently recruiting, with further details available on the ClinicalTrials portal.