Abbvie ((ABBV)), Abbvie (($CC:ABBV.CUR)) announced an update on their ongoing clinical study.
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AbbVie is conducting a clinical study to evaluate the risk of Tumor Lysis Syndrome (TLS) in adult participants with previously untreated Chronic Lymphocytic Leukemia (CLL). The study aims to assess the safety of combining oral Venetoclax with either intravenously infused Obinutuzumab or oral Acalabrutinib. This research is significant as it explores optimizing treatment initiation for CLL, potentially improving patient outcomes.
The interventions being tested include Venetoclax, an oral tablet, in combination with either Obinutuzumab, administered intravenously, or Acalabrutinib, also an oral tablet. These combinations are intended to treat CLL more effectively.
The study is designed as an interventional, randomized, parallel assignment with no masking, focusing on treatment as its primary purpose. Participants are divided into four groups, each receiving different dosing schemes of the drug combinations.
The study began on August 5, 2024, with an estimated primary completion date in 2025 and an overall completion date in 2026. The latest update was submitted on July 1, 2025, indicating ongoing recruitment and study progress.
This study update could influence AbbVie’s stock performance and investor sentiment by showcasing the company’s commitment to advancing CLL treatment. In the competitive landscape of oncology, successful outcomes could strengthen AbbVie’s market position.
The study is ongoing, and further details are available on the ClinicalTrials portal.