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Baker Bros. Advisors Lp Insider Profile

144 Followers
Baker Bros. Advisors Lp, Ten Percent Owner at BioCryst, holds 425.01K shares in Kala Pharmaceuticals (Ticker: KALA), holds 28.78M shares in Incyte (Ticker: INCY), holds 7.21M shares in Celcuity (Ticker: CELC). Most recently, Baker Bros. Advisors Lp Sold ― shares of Kala Pharmaceuticals on Oct 02, 2025 for an estimated value of $1.05M.
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Baker Bros. Advisors Lp

Baker Bros. Advisors Lp
BioCryst (BCRX)
Ten Percent Owner

Ranked #405 out of 103,781 Corporate Insiders

Profitable Transactions

53%
51 out of 96 Profitable Transactions

Average Return

+25.70%
Average return per transaction
Time Frame
1 Year
Compare to
No Benchmark

Insider Holdings

$9B
33.63%
27.54%
9.36%
9.33%
20.14% Others
A breakdown of Baker Bros. Advisors Lp's holdings

Insider Roles

BeOne Medicines
(ONC)
Director
Incyte
(INCY)
Director, Ten Percent Owner
ACADIA Pharmaceuticals
(ACAD)
Director, Ten Percent Owner
Madrigal Pharmaceuticals
(MDGL)
Director
+21 other positions
Roles that Baker Bros. Advisors Lp holds in companies

Most Profitable Insider Trade

Stock:
Invitae
(NVTAQ)
Rating:Informative Buy
Date:Mar 29, 2018 - Mar 29, 2019
Return:+399.30%
The most profitable trade made by Baker Bros. Advisors Lp

Baker Bros. Advisors Lp's Trading History

Company Name
Last Transaction Date
Insider Position
Last Transaction
Last Transaction Amount
Holding Value
BioCryst
Aug 16, 2016
Ten Percent Owner
Informative Sell
20.25M
$104.69M
BLCM
Bellicum Pharmaceuticals
Nov 24, 2023
Uninformative Buy
$160.49K
BeOne Medicines
May 22, 2025
Director
Uninformative Buy
$3.06B
ACGN
Aceragen
Jul 03, 2019
Uninformative Buy
15.47K
$1.65M
ALXN
Alexion Pharmaceuticals
May 18, 2020
Uninformative Buy
$1.47B
Kiniksa Pharmaceuticals
Jun 05, 2025
Director
Uninformative Buy
$105.54M
Hookipa Pharma
Apr 23, 2019
Former 10% owner
Informative Buy
12.50M
$736.19K
Kodiak Sciences
Jun 06, 2022
Director, Ten Percent Owner
Informative Buy
4.45M
$227.22M
IGMS
IGM Biosciences
Aug 18, 2025
Uninformative Sell
$0.00
BCEL
Atreca
Oct 23, 2023
Informative Sell
109.90K
$267.40K
Zymeworks
Director
Prelude Therapeutics
Jan 29, 2021
Director, Ten Percent Owner
Uninformative Buy
133.33K
$13.32M
Spyre Therapeutics
Director
Talis Biomedical
Nov 19, 2021
Director, Ten Percent Owner
Informative Buy
218.00K
$11.44M
TScan Therapeutics
May 12, 2022
Director
Informative Buy
2.56M
$4.98M
Entrada Therapeutics Inc
Jun 06, 2022
Ten Percent Owner
Informative Buy
260.68K
$26.33M
DBV Technologies SA - American
Jun 13, 2022
Director, Ten Percent Owner
Uninformative Buy
$415.67M
Madrigal Pharmaceuticals
Aug 20, 2025
Director
Informative Buy
24.98M
$849.86M
vTv Therapeutics
Sep 05, 2025
Director
Uninformative Buy
$3.07M
Kymera Therapeutics
Jun 30, 2025
Director
Informative Buy
28.84M
$348.20M
Bicycle Therapeutics
Jan 06, 2025
Director, Ten Percent Owner
Uninformative Buy
$80.00M
Immunocore Holdings
Mar 19, 2025
Director
Informative Buy
23.99M
$73.37M
Kala Pharmaceuticals
Oct 02, 2025
Former 10% owner
Informative Sell
1.05M
$697.01K
Replimune Group
Director, Ten Percent Owner
Denali Therapeutics
Jun 05, 2025
Director
Uninformative Buy
$50.90M
Celcuity
Sep 10, 2025
Ten Percent Owner
Informative Buy
9.57M
$354.91M
MRTX
Mirati Therapeutics
Nov 13, 2017
Informative Buy
2.20M
$2.13M
Neurogene
Oct 10, 2023
Director, Former 10% Owner
Uninformative Buy
$10.65M
NVTAQ
Invitae
Mar 29, 2018
Informative Buy
5.00M
$83.09K
ACADIA Pharmaceuticals
Jun 02, 2025
Director, Ten Percent Owner
Uninformative Buy
$852.37M
Xoma
Jul 23, 2015
Former 10% owner
Informative Sell
11.99M
$3.36M
GHDX
Genomic Health
Oct 03, 2019
Uninformative Buy
124.47K
$484.81M
Incyte
Oct 02, 2025
Director, Ten Percent Owner
Uninformative Buy
$2.51B
SGEN
Seagen
Jun 02, 2023
Uninformative Buy
$9.84B
GEVA
Synageva
List of latest transactions for each holding click on a transaction to see Baker Bros. Advisors Lp's performance on stock

Baker Bros. Advisors Lp insider profile FAQ

What is the percentage of profitable transactions made by Baker Bros. Advisors Lp?
The percentage of profitable transactions made by Baker Bros. Advisors Lp is 53%.
    What is the average return per transaction made by Baker Bros. Advisors Lp?
    The average return per transaction made by Baker Bros. Advisors Lp is 25.70%.
      What stocks does Baker Bros. Advisors Lp hold?
      Baker Bros. Advisors Lp holds: BCRX, BLCM, ONC, ACGN, ALXN, KNSA, HOOK, KOD, IGMS, BCEL, ZYME, PRLD, SYRE, TLIS, TCRX, TRDA, DBVT, MDGL, VTVT, KYMR, BCYC, IMCR, KALA, REPL, DNLI, CELC, MRTX, NGNE, NVTAQ, ACAD, XOMA, GHDX, INCY, SGEN, GEVA stocks.
        What was Baker Bros. Advisors Lp’s latest transaction?
        Baker Bros. Advisors Lp latest transaction was an Informative Sell of $1.05M.
          What was Baker Bros. Advisors Lp's most profitable transaction?
          Baker Bros. Advisors Lp’s most profitable transaction was an Informative Buy of NVTAQ stock on March 29, 2018. The return on the trade was 399.30%.
            What is Baker Bros. Advisors Lp's role in BioCryst?
            Baker Bros. Advisors Lp's role in BioCryst is Ten Percent Owner.
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