Clinical Trial MilestonesThe Phase 2a study of Risvodetinib is advancing, focusing on both motor and non-motor Parkinson's symptoms and the reduction of alpha-synuclein aggregates, which could indicate a disease-modifying effect.
Drug Development ProgressRisvodetinib, a promising treatment for Parkinson’s disease, shows strong potential with over 25 times stronger inhibition of c-Abl than its predecessor, and modifications for enhanced brain penetration and selectivity.
Regulatory AdvancementsIkT-001Pro, targeting multiple oncology indications, has completed bioequivalence studies, with the FDA providing clear requirements for NDA filing, marking a definitive step forward in the drug’s development process.