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PainReform (PRFX) AI Stock Analysis

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PRFX

PainReform

(NASDAQ:PRFX)

Select Model
Rating:37Underperform
Price Target:$0.81â–²(3.96% Upside)
Action:reiterated
Date:10/20/26

PRFX scores at the bottom of the range, driven primarily by very weak financial performance: no meaningful revenue, an ~$8.9 million TTM net loss, and operating cash burn that roughly doubled to ~$7.4 million, leaving the company dependent on external financing and exposing shareholders to further dilution. A debt-free balance sheet with ~$15.9 million of equity provides some flexibility but only a limited runway at the current burn rate. Technicals reinforce the caution, with the stock trading well below all key moving averages and negative MACD signaling an entrenched downtrend, though deeply oversold readings leave room for short-term bounces. Valuation provides no cushion given negative earnings and no dividend. With no earnings call commentary or corporate events available, the score rests on fundamentals, trend, and valuation — all of which point to elevated, speculative risk.

Positive Factors
Low leverageMinimal debt limits borrowing-related financial risk and preserves flexibility for research, clinical development, and commercialization. Although losses remain substantial, the low-leverage structure gives management more room to pursue strategic priorities without heavy interest or refinancing burdens.
Negative Factors
Severe early-stage lossesRevenue remains immaterial relative to operating costs, and large EBIT and net losses show that the business has not yet reached commercial scale. Persistent losses reduce financial resilience and make future performance dependent on successful development and commercialization of products.

PainReform (PRFX) vs. SPDR S&P 500 ETF (SPY)

-100%-75%-50%-25%0%25%50%PRFX-81.31%SPY+14.55%Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26Nov '26
Market Cap
$63.02K
Dividend Yield
―
Average Volume (3M)
229.28K
Price to Earnings (P/E)
-0.1
Beta (1Y)
1.64
Revenue Growth
―
EPS Growth
―
Country
US
Employees
7
Sector
Healthcare
Sector Strength
51
Industry
Drug Manufacturers - Specialty & Generic

PainReform Business Overview & Revenue Model

Company Description

PRF Technologies Ltd. operates as a specialized pharmaceutical company, currently in the clinical development stage, with a focus on pioneering treatments that deliver sustained post-surgical pain management. Central to its pipeline is PRF-110, a dis...

PainReform Financial Statement Overview

Summary

Financials reflect a pre-commercial development-stage biotech with essentially no revenue (~$40K TTM), a net loss of roughly $8.9 million, and negative gross profit. Operating cash burn nearly doubled year over year to about -$7.4 million, with free cash flow tracking losses almost one-for-one, confirming real cash losses. The lone bright spot is a virtually debt-free balance sheet with ~$15.9 million of equity funding ~83% of assets, but that cushion was built through share issuance rather than profits, implying limited runway at the current burn rate and ongoing dilution risk. Income statement (8) and cash flow (9) scores are extremely weak; the balance sheet (45) only partially offsets them.

Income Statement

8Very Negative

Balance Sheet

45Neutral

Cash Flow

9Very Negative
Financial statement breakdown
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue39.50K17.00K0086.00K0
Gross Profit-121.50K-827.00K-16.00K-15.00K71.00K―
EBITDA-7.39M-4.21M-14.55M-9.57M-8.76M-7.22M
Net Income-8.90M-4.84M-14.59M-9.34M-8.79M-7.25M
Balance Sheet
Total Assets19.09M12.00M4.53M9.93M12.33M19.07M
Cash, Cash Equivalents and Short-Term Investments11.54M4.17M4.26M8.03M4.10M16.54M
Total Debt50.00K21.00K45.00K86.00K00
Total Liabilities2.62M2.71M2.70M2.69M1.31M991.00K
Stockholders Equity15.87M8.54M1.82M7.24M11.02M18.08M
Cash Flow
Free Cash Flow-7.38M-3.96M-12.63M-6.69M-6.46M-6.60M
Operating Cash Flow-7.38M-3.96M-12.62M-6.68M-6.46M-6.55M
Investing Cash Flow-3.45M-982.00K-13.00K5.99M-6.01M-50.00K
Financing Cash Flow14.93M3.82M8.86M4.62M07.48M

PainReform Technical Analysis

Technical Analysis SentimentNegative
Last Price0.78

Price Trends

50DMA0.85Negative
100DMA1.00Negative
200DMA1.66Negative

Market Momentum

MACD-0.02Negative
RSI47.81Neutral
STOCH52.44Neutral

Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For PRFX, the sentiment is Negative. The current price of 0.78 is above the 20-day moving average (MA) of 0.76, below the 50-day MA of 0.85, and below the 200-day MA of 1.66, indicating a neutral trend. The MACD of -0.02 indicates Negative momentum. The RSI at 47.81 is Neutral, neither overbought nor oversold. The STOCH value of 52.44 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for PRFX.

PainReform Risk Analysis

PainReform disclosed 46 risk factors in its most recent earnings report. PainReform reported the most risks in the "Finance & Corporate" category.

Higher RiskSector Avg.Lower RiskFinance & CorporateTech & InnovationLegal & RegulatoryProductionAbility to SellMacro & Political
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy

Latest Risks Added

0 New Risks

PainReform Peers Comparison

Overall Rating

UnderperformOutperform
Sector (51)

Financial Indicators

PRFX against its peers
NameOverall RatingMarket CapP/E RatioROEDividend YieldRevenue GrowthEPS Growth
CPHICPHI56Neutral$22.29M-0.51-17.14%―-10.97%71.83%
Sector *51Neutral$7.86B-0.30-43.30%2.27%22.53%-2.21%
COSMCOSM43Neutral$16.30M-4.91-118.89%―33.82%34.05%
RDHLRDHL42Neutral$3.33M-0.38-438.17%―――
PRFXPRFX37Underperform$2.38M-0.07-72.87%―――
SHPHSHPH32Underperform$21.58M-0.15-156.78%――94.90%

* Healthcare Sector Average

Performance Comparison

0%200%400%PRFXCPHIRDHLCOSMSHPHDec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26Nov '26
PRFX and its peers over the selected period
Show on chartTickerCompany NamePriceChange% Change
PRFXPainreform Ltd.0.78-3.64-82.30%
CPHIChina Pharma0.52-0.98-65.47%
RDHLRedHill Biopharma Ltd0.38-0.67-63.94%
COSMCosmos Holdings 3.24-10.76-76.86%
SHPHShuttle Pharmaceuticals Holdings, Inc.4.53-14.67-76.41%

PainReform Corporate Events

PRF Technologies Faces Court Petition From Activist Shareholder

Nov 5, 2026

On November 2, 2026, S.H.N. Financial Investments petitioned the Tel Aviv District Court to compel PRF Technologies Ltd. to convene a special shareholder meeting. S.H.N. seeks to remove three non-external directors and elect its own nominees, while a...

PRF Technologies Signs Term Sheet With Dotz Nano for GridFeed Collaboration

Nov 3, 2026

PRF Technologies, a healthcare and sustainable-energy technology company, develops reformulated therapeutics and AI software for renewable-energy forecasting, battery storage optimization and electricity-market trading. On November 3, 2026, it announ...

PRF Technologies Highlights $11 Million Cash, Phase 2 OcuRingâ„¢-K Trial Plans and GridFeed AI Data Center Strategy

Oct 23, 2026

On October 23, 2026, PRF Technologies reported preliminary consolidated cash, including short-term deposits, of about $11.0 million and total liabilities of roughly $2.5 million as of September 30, 2026, after raising approximately $10.5 million in g...

PRF Technologies Faces Board Shake-Up Bid from 5.7% Shareholder S.H.N.

Sep 28, 2026

On September 24, 2026, PRF Technologies Ltd. received a letter from S.H.N. Financial Investments Ltd., which claims to hold about 5.7% of the company’s voting rights, calling for a special general meeting to remove all directors other than the extern...

PRF Technologies Targets AI Data Centers With GridFeed Power Optimization Push

Sep 16, 2026

On September 16, 2026, PRF Technologies announced that GridFeed, its AI-driven energy intelligence and optimization platform, is targeting AI and hyperscale data centers as a strategic growth market amid surging global power demand. Citing Internatio...

PRF Technologies Spins Out GridFeed Unit to Drive AI Renewable Energy Trading Partnerships

Sep 9, 2026

PRF Technologies Ltd., a Tel Aviv-based company listed on Nasdaq, straddles healthcare and sustainable energy through reformulated pain-management drugs and AI-powered energy optimization platforms. Its pharma portfolio includes candidates like OcuRi...

PRF Technologies Posts Wider First-Half 2026 Loss but Bolsters Cash and Equity

Sep 3, 2026

On September 3, 2026, PRF Technologies reported unaudited financial results for the six months ended June 30, 2026, highlighting a modest $14,000 in revenue and an operating loss of $2.5 million. The company’s net loss before tax widened to $2.9 mill...

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.

Date of analysis: Oct 20, 2026