Adverse Drug ReactionsTwo EHE patients experienced Grade 3-4 liver enzyme elevation, one deemed dose limiting.
Clinical Trial ResultsUpon release of the data, IMRX stock fell stemming from a lack of efficacy at the RP2D dose level, bringing into question IMM-1-104’s mechanistic rationale.
Drug Efficacy ConcernsWhile IMM-1-104 was designed to have a short plasma half-life, the strategy's improvement on safety seems thus far to come at the cost of efficacy.