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Beyondspring (BYSI) AI Stock Analysis

BYSI

Beyondspring

(NASDAQ:BYSI)

Select Model
Rating:41Neutral
Price Target:$0.49â–¼(-23.33% Downside)
Action:reiterated
Date:10/14/26

BYSI scores near the low end of the range, driven primarily by a severely strained financial position: zero revenue, negative stockholders' equity of -$32M, a shrinking $26M asset base, and roughly $20M of annual cash burn that raises going-concern and financing questions. Technicals reinforce the caution, with the stock trading well below all key moving averages and negative MACD momentum. Valuation provides no anchor given negative earnings and no dividend. Partially offsetting these risks are a dramatic reduction in losses and cash burn, a capital-efficient China partnership for the Phase 3 DUBLIN-4 trial, FDA Fast Track designation, and an ATM facility for added funding flexibility — but dual Nasdaq listing-compliance deficiencies make this a highly speculative, binary situation dependent on pipeline outcomes.

Positive Factors
Narrowing lossesThe substantial reduction in annual losses indicates improving cost discipline and a lower burden from ongoing operations than in earlier years. Although Beyondspring remains unprofitable, continued improvement could extend available resources and make future financing more effective.
Negative Factors
Pre-commercial business modelThe absence of recurring product revenue leaves Beyondspring dependent on clinical and regulatory outcomes before it can establish commercial operating leverage. This makes earnings visibility weak and means future funding needs remain closely tied to development progress.

Beyondspring (BYSI) vs. SPDR S&P 500 ETF (SPY)

-80%-60%-40%-20%0%20%BYSI-68.17%SPY+11.79%Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26
Market Cap
$26.47M
Dividend Yield
―
Average Volume (3M)
859.40K
Price to Earnings (P/E)
-3.9
Beta (1Y)
-0.29
Revenue Growth
―
EPS Growth
―
Country
US
Employees
44
Sector
Healthcare
Sector Strength
51
Industry
Biotechnology

Beyondspring Business Overview & Revenue Model

Company Description

BeyondSpring Inc. is a clinical-stage biopharmaceutical company focused on developing novel cancer treatments. Its flagship product is Plinabulin, a selective immune-modulating and microtubule-binding agent. Plinabulin has successfully advanced throu...

How the Company Makes Money

As a clinical-stage biopharmaceutical company, Beyondspring has historically not relied on recurring product sales as its primary source of revenue because its key product candidates (including plinabulin) have been in development and subject to clin...

Beyondspring Financial Statement Overview

Summary

The financial profile is extremely weak. BeyondSpring generates no revenue, has posted continuous net losses, and carries deeply negative stockholders' equity of -$32.2M with total assets shrinking from $117M (2020) to $25.9M (2025). Operating cash outflows of roughly $20M per year against this shrinking asset base raise clear going-concern risk. The only positives are sharply reduced losses (from -$64M in 2021 to -$8.5M in 2025), narrowed cash burn, and minimal debt of $320K — meaningful cost discipline, but not enough to offset the absence of any revenue base.

Income Statement

12Very Negative

Balance Sheet

8Very Negative

Cash Flow

15Very Negative
Financial statement breakdown
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue00001.35M1.35M
Gross Profit-38.00K-87.00K0-302.00K1.35M1.35M
EBITDA-7.87M-8.54M-8.48M-13.62M-35.87M-64.49M
Net Income-6.68M-7.99M-11.12M-21.03M-33.28M-64.18M
Balance Sheet
Total Assets14.61M25.93M34.31M24.81M46.22M81.65M
Cash, Cash Equivalents and Short-Term Investments6.53M12.56M2.92M15.34M37.27M72.37M
Total Debt171.00K320.00K589.00K847.00K4.96M3.58M
Total Liabilities50.63M49.92M48.60M48.27M49.23M60.73M
Stockholders Equity-35.57M-32.16M-32.90M-26.80M-5.98M26.68M
Cash Flow
Free Cash Flow-17.05M-20.07M-16.67M-16.57M-28.18M-50.09M
Operating Cash Flow-17.05M-20.02M-16.44M-16.47M-28.15M-47.24M
Investing Cash Flow1.26M13.48M-12.01M-100.00K18.25M-20.41M
Financing Cash Flow-2.24M2.27M26.79M4,0003.43M1,000

Beyondspring Technical Analysis

Technical Analysis SentimentNeutral
Last Price0.64

Price Trends

50DMA0.66Negative
100DMA0.98Negative
200DMA1.27Negative

Market Momentum

MACD-0.05Negative
RSI54.08Neutral
STOCH66.60Neutral

Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For BYSI, the sentiment is Neutral. The current price of 0.64 is above the 20-day moving average (MA) of 0.56, below the 50-day MA of 0.66, and below the 200-day MA of 1.27, indicating a neutral trend. The MACD of -0.05 indicates Negative momentum. The RSI at 54.08 is Neutral, neither overbought nor oversold. The STOCH value of 66.60 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for BYSI.

Beyondspring Risk Analysis

Beyondspring disclosed 87 risk factors in its most recent earnings report. Beyondspring reported the most risks in the "Legal & Regulatory" category.

Higher RiskSector Avg.Lower RiskFinance & CorporateTech & InnovationLegal & RegulatoryProductionAbility to SellMacro & Political
Legal & Regulatory - Litigation, compliance, new legislation, and taxation risks

Latest Risks Added

1 New Risk
1.We will depend on our ability to obtain necessary financing to fund our working capital requirement to continue as a going concern.Q2, 2026

Beyondspring Peers Comparison

Overall Rating

UnderperformOutperform
Sector (51)

Financial Indicators

BYSI against its peers
NameOverall RatingMarket CapP/E RatioROEDividend YieldRevenue GrowthEPS Growth
XFORXFOR55Neutral$332.14M-2.79-63.05%―-51.65%91.93%
PRLDPRLD53Neutral$309.64M-4.91-75.35%―220.34%55.73%
Sector *51Neutral$7.86B-0.30-43.30%2.27%22.53%-2.21%
GANXGANX48Neutral$49.32M-2.26-161.58%――23.02%
ABVCABVC43Neutral$26.69M-3.39-71.47%―-100.00%-55.90%
BYSIBYSI41Neutral$26.47M-3.9019.96%―――

* Healthcare Sector Average

Performance Comparison

-50%0%50%100%BYSIXFORABVCPRLDGANXDec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26
BYSI and its peers over the selected period
Show on chartTickerCompany NamePriceChange% Change
BYSIBeyondspring0.64-1.43-68.94%
XFORX4 Pharmaceuticals3.35-0.74-18.09%
ABVCABVC BioPharma, Inc.1.00-1.96-66.22%
PRLDPrelude Therapeutics, Inc.3.88-0.10-2.51%
GANXGain Therapeutics, Inc.1.13-0.71-38.59%

Beyondspring Corporate Events

Business Operations and StrategyShareholder Meetings

BeyondSpring Shareholders Ratify 2026 Auditor Appointment

Positive
Oct 13, 2026

BeyondSpring Inc. held its 2026 annual meeting of shareholders on October 13, 2026, with 20,905,921 ordinary shares present or represented by proxy, amounting to approximately 50.84% of the 41,119,820 shares outstanding and entitled to vote as of the...

Business Operations and StrategyFinancial DisclosuresM&A Transactions

BeyondSpring Divests China Assets, Refocuses on Data Partnerships

Neutral
Oct 6, 2026

On September 30, 2026, BeyondSpring completed the sale of all its ownership interests in BeyondSpring Ltd., which indirectly held its majority stake in China-based Dalian Wanchunbulin Pharmaceuticals, to Hong Kong’s Biolin Investment. The trans...

Delistings and Listing ChangesRegulatory Filings and Compliance

BeyondSpring Faces Nasdaq Listing Compliance Risk

Negative
Oct 2, 2026

On September 29, 2026, BeyondSpring Inc. disclosed that Nasdaq notified the company its market value of listed securities had fallen below the $35 million minimum for 30 straight business days, breaching the Capital Market’s continued listing s...

Business Operations and StrategyPrivate Placements and Financing

BeyondSpring launches ATM program to bolster financing

Positive
Sep 29, 2026

On September 28 and 29, 2026, BeyondSpring entered into a share purchase and strategic collaboration with Biolin Investment and its Chinese subsidiary Bulin, and launched an at-the-market equity program. Under the collaboration, BeyondSpring will sel...

Delistings and Listing ChangesRegulatory Filings and Compliance

BeyondSpring Faces Nasdaq Noncompliance Over Minimum Bid Price

Negative
Sep 18, 2026

On September 17, 2026, BeyondSpring Inc. received notice from Nasdaq that its ordinary shares had traded below the $1.00 minimum bid price for 30 consecutive business days, placing the company out of compliance with Nasdaq’s continued listing r...

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.

Date of analysis: Oct 13, 2026