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Beyondspring (BYSI) AI Stock Analysis

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BYSI

Beyondspring

(NASDAQ:BYSI)

Select Model
Rating:42Neutral
Price Target:$0.77â–²(28.62% Upside)
Action:reiterated
Date:11/03/26

BYSI scores low primarily due to severe financial weakness: zero revenue, negative equity of -$32M, roughly $20M of annual cash burn, and a shrinking asset base that raises going-concern risk. Dual Nasdaq compliance notices add delisting risk, and the negative P/E with no dividend offers no valuation cushion. Partial offsets include a sharply reduced loss and burn trajectory, the capital-efficient Biolin partnership funding the China portion of the Phase 3 DUBLIN-4 trial, FDA Fast Track designation, and short-term price stabilization above the 20- and 50-day averages. Overall, this remains a highly speculative, binary pipeline-driven situation.

Positive Factors
Capital-efficient trial collaborationThe China-focused collaboration can reduce BeyondSpring’s direct funding burden for a major Phase 3 program while preserving access to trial data and commercialization rights outside Greater China. That structure may extend financial runway and improve capital efficiency as the company advances global registration efforts.
Negative Factors
No recurring commercial revenueWith no meaningful recurring product revenue, BeyondSpring remains dependent on clinical and regulatory progress before it can establish a self-funded commercial model. This limits operating leverage, keeps earnings visibility weak, and makes future financial performance highly dependent on development outcomes.

Beyondspring (BYSI) vs. SPDR S&P 500 ETF (SPY)

-80%-60%-40%-20%0%20%BYSI-70.68%SPY+13.89%Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26Nov '26
Market Cap
$24.71M
Dividend Yield
―
Average Volume (3M)
281.28K
Price to Earnings (P/E)
-3.8
Beta (1Y)
-0.16
Revenue Growth
―
EPS Growth
―
Country
US
Employees
44
Sector
Healthcare
Sector Strength
51
Industry
Biotechnology

Beyondspring Business Overview & Revenue Model

Company Description

BeyondSpring Inc. is a clinical-stage biopharmaceutical company focused on developing novel cancer treatments. Its flagship product is Plinabulin, a selective immune-modulating and microtubule-binding agent. Plinabulin has successfully advanced throu...

How the Company Makes Money

As a clinical-stage biopharmaceutical company, Beyondspring has historically not relied on recurring product sales as its primary source of revenue because its key product candidates (including plinabulin) have been in development and subject to clin...

Beyondspring Financial Statement Overview

Summary

Financials are very weak. BeyondSpring generates zero revenue, posted a net loss of $8.5M in 2025, and carries deeply negative stockholders' equity of -$32.2M with a shrinking asset base of just $25.9M. Operating cash outflows of roughly $20M per year against this limited asset base raise serious going-concern and financing risk. The only positives are sharply reduced losses (from -$64M in 2021), narrowing cash burn, and minimal debt of $320K — meaningful cost discipline, but not enough to offset a fundamentally distressed balance sheet.

Income Statement

12Very Negative

Balance Sheet

8Very Negative

Cash Flow

15Very Negative
Financial statement breakdown
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue00001.35M1.35M
Gross Profit-38.00K-87.00K0-302.00K1.35M1.35M
EBITDA-7.87M-8.54M-8.48M-13.62M-35.87M-64.49M
Net Income-6.68M-7.99M-11.12M-21.03M-33.28M-64.18M
Balance Sheet
Total Assets14.61M25.93M34.31M24.81M46.22M81.65M
Cash, Cash Equivalents and Short-Term Investments6.53M12.56M2.92M15.34M37.27M72.37M
Total Debt171.00K320.00K589.00K847.00K4.96M3.58M
Total Liabilities50.63M49.92M48.60M48.27M49.23M60.73M
Stockholders Equity-35.57M-32.16M-32.90M-26.80M-5.98M26.68M
Cash Flow
Free Cash Flow-17.05M-20.07M-16.67M-16.57M-28.18M-50.09M
Operating Cash Flow-17.05M-20.02M-16.44M-16.47M-28.15M-47.24M
Investing Cash Flow1.26M13.48M-12.01M-100.00K18.25M-20.41M
Financing Cash Flow-2.24M2.27M26.79M4,0003.43M1,000

Beyondspring Technical Analysis

Technical Analysis SentimentNegative
Last Price0.60

Price Trends

50DMA0.66Negative
100DMA0.89Negative
200DMA1.23Negative

Market Momentum

MACD-0.01Negative
RSI48.72Neutral
STOCH23.98Neutral

Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For BYSI, the sentiment is Negative. The current price of 0.60 is above the 20-day moving average (MA) of 0.57, below the 50-day MA of 0.66, and below the 200-day MA of 1.23, indicating a neutral trend. The MACD of -0.01 indicates Negative momentum. The RSI at 48.72 is Neutral, neither overbought nor oversold. The STOCH value of 23.98 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for BYSI.

Beyondspring Risk Analysis

Beyondspring disclosed 87 risk factors in its most recent earnings report. Beyondspring reported the most risks in the "Legal & Regulatory" category.

Higher RiskSector Avg.Lower RiskFinance & CorporateTech & InnovationLegal & RegulatoryProductionAbility to SellMacro & Political
Legal & Regulatory - Litigation, compliance, new legislation, and taxation risks

Latest Risks Added

3 New Risks
1.We will depend on our ability to obtain necessary financing to fund our working capital requirement to continue as a going concern.Q2, 2026
2.We and our major shareholders have been, and may in the future become, subject to claims, litigation, arbitration and investigations, any of which may require significant management attention, could result in significant legal expenses and may result in unfavorable outcomes, all or any of which could have a material adverse impact on our financial condition and results of operations, harm our reputation or otherwise negatively impact our business.Q4, 2023
3.We will depend on our ability to obtain necessary financing to fund our working capital requirement to continue as a going concern.Q4, 2023

Beyondspring Peers Comparison

Overall Rating

UnderperformOutperform
Sector (51)

Financial Indicators

BYSI against its peers
NameOverall RatingMarket CapP/E RatioROEDividend YieldRevenue GrowthEPS Growth
Sector *51Neutral$7.86B-0.30-43.30%2.27%22.53%-2.21%
XFORXFOR43Neutral$329.83M-4.69-49.62%―-50.08%93.36%
BYSIBYSI42Neutral$26.47M-3.8319.96%―――
GANXGANX41Neutral$49.42M-2.60-133.17%――33.17%
ABVCABVC39Underperform$26.76M-4.50-41.67%―-100.00%39.04%
PRLDPRLD38Underperform$301.66M-4.49-75.35%―220.34%55.73%

* Healthcare Sector Average

Performance Comparison

0%100%200%300%BYSIXFORABVCPRLDGANXDec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26Nov '26
BYSI and its peers over the selected period
Show on chartTickerCompany NamePriceChange% Change
BYSIBeyondspring0.60-1.49-71.24%
XFORX4 Pharmaceuticals3.17-0.49-13.39%
ABVCABVC BioPharma, Inc.0.96-1.96-67.02%
PRLDPrelude Therapeutics, Inc.3.522.00131.58%
GANXGain Therapeutics, Inc.1.08-1.75-61.84%

Beyondspring Corporate Events

Business Operations and StrategyShareholder Meetings

BeyondSpring Shareholders Ratify 2026 Auditor Appointment

Positive
Oct 13, 2026

BeyondSpring Inc. held its 2026 annual meeting of shareholders on October 13, 2026, with 20,905,921 ordinary shares present or represented by proxy, amounting to approximately 50.84% of the 41,119,820 shares outstanding and entitled to vote as of the...

Business Operations and StrategyFinancial DisclosuresM&A Transactions

BeyondSpring Divests China Assets, Refocuses on Data Partnerships

Neutral
Oct 6, 2026

On September 30, 2026, BeyondSpring completed the sale of all its ownership interests in BeyondSpring Ltd., which indirectly held its majority stake in China-based Dalian Wanchunbulin Pharmaceuticals, to Hong Kong’s Biolin Investment. The transaction...

Delistings and Listing ChangesRegulatory Filings and Compliance

BeyondSpring Faces Nasdaq Listing Compliance Risk

Negative
Oct 2, 2026

On September 29, 2026, BeyondSpring Inc. disclosed that Nasdaq notified the company its market value of listed securities had fallen below the $35 million minimum for 30 straight business days, breaching the Capital Market’s continued listing standar...

Business Operations and StrategyPrivate Placements and Financing

BeyondSpring launches ATM program to bolster financing

Positive
Sep 29, 2026

On September 28 and 29, 2026, BeyondSpring entered into a share purchase and strategic collaboration with Biolin Investment and its Chinese subsidiary Bulin, and launched an at-the-market equity program. Under the collaboration, BeyondSpring will sel...

Delistings and Listing ChangesRegulatory Filings and Compliance

BeyondSpring Faces Nasdaq Noncompliance Over Minimum Bid Price

Negative
Sep 18, 2026

On September 17, 2026, BeyondSpring Inc. received notice from Nasdaq that its ordinary shares had traded below the $1.00 minimum bid price for 30 consecutive business days, placing the company out of compliance with Nasdaq’s continued listing require...

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.

Date of analysis: Nov 02, 2026