Competitive LandscapeCompeting molecules from Repare, AstraZeneca, and Bayer have faced toxicity issues, particularly with anemia, potentially limiting their therapeutic use.
Corporate ActionsCompany completed 1:20 reverse split, typically a move made by companies facing stock price pressures or to maintain compliance with exchange listing requirements.
Drug Development ConcernsZentalis' Zn-c3 faces toxicity issues due to off-target PLK activity, necessitating intermittent dosing which is less ideal than continuous dosing.