Cash Position: As of September 30, cash, cash equivalents, and marketable securities were $132.4M . "We made tremendous progress across our portfolio in recent months, demonstrating the power of our business development platform to identify transformative science, as well as the ability of our team to efficiently advance clinical trials across diverse therapeutic areas," said Martin Mackay, Ph.D., Chief Executive Officer. "Earlier this morning, we announced positive topline data from our Phase 1 trial of RLYB116, which we believe validate RLYB116 as a highly innovative, differentiated inhibitor of complement component 5 (C5), with the potential to address clinical and commercial challenges that have limited the reach of first-generation programs. We look forward to initiating a multiple ascending dose Phase 1 study in the first quarter of 2023 and, ultimately, to developing RLYB116 for a broad range of complement-mediated diseases." Dr. Mackay continued, "Moving to the rest of our pipeline, in September 2022, we announced preliminary platelet elimination results from our ongoing Phase 1b proof-of-concept study for RLYB212, which is in development for the prevention of fetal and neonatal alloimmune thrombocytopenia. These data showed rapid and complete elimination of transfused platelets in all subjects to date, with a greater than 90 percent reduction of the mean platelet elimination half-life compared to placebo. We expect to discuss the proof-of-concept data in the first quarter of 2023. Our other preclinical programs are also advancing according to our plan. We expect our existing capital will be sufficient to fund our operating expenses and capital expenditure requirements into the first quarter of 2024."
Published first on TheFly
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