Paratek Pharmaceuticals announces data from pilot efficacy study on NUZYRA

Paratek Pharmaceuticals announced positive top line data from a pilot rabbit efficacy study evaluating NUZYRA’s effectiveness in the treatment of pulmonary anthrax. In the study, a 100% survival rate was observed in omadacycline-treated rabbits at the specified endpoint of 35-45 days post Bacillus anthracis challenge, while all rabbits treated with placebo died due to anthrax infection within three days. Positive top line data from this study triggered the second procurement under the Company’s Project BioShield Contract with Biomedical Advanced Research and Development Authority, part of the Administration for Strategic Preparedness and Response within the U.S. Department of Health and Human Services. Accordingly, Paratek has delivered 2,500 treatment courses of NUZYRA to BARDA. The acceptance of this procurement allows the Company to recognize $38.1 million in revenue, comprised of $36.4 million from BARDA and approximately $1.7 million in deferred revenue related to postmarketing commitments under the Project BioShield contract. "This positive top line data represents further validation of NUZYRA’s potential to treat pulmonary anthrax as well as the continued commitment by BARDA to our ongoing partnership," said Randy Brenner, chief development and regulatory officer, Paratek. "We believe that NUZYRA is well-positioned to help address potential public health emergencies, including biothreats and pandemics."