electroCore announces data from abstract on nVNS

electroCore announced top line data from an abstract being presented as an oral podium presentation at the 2023 American College of Gastroenterology Annual Meeting held in Vancouver, Canada from October 23-25, 2023 regarding the potential for Non-invasive Vagus Nerve Stimulation, nVNS, to decrease the use of acute rescue medications for exacerbations of nausea due to Gastroparesis or Functional Dyspepsia. This pilot study included patients greater than or equal to15 years of age with ongoing GP or FD symptoms for a period of greater than or equal to3 months. The primary endpoint was reducing the use of antinausea medications by using nVNS as the primary rescue treatment for nausea exacerbations. Exploratory endpoints included changes in GI, autonomic, and psychological symptoms via standardized questionnaires. The study showed nVNS reduced the use of rescue pills per day by more than 50%. This benefit was maintained throughout each 4-week treatment period of the crossover study as well as during the two, two-week, washout periods. Exploratory endpoints revealed robust improvements in abdominal pain, reflux, indigestion, and constipation. Depression levels, as measured by the Beck Index, improved, and Migraine scores improved with the subjects using fewer headache/migraine pills per day during the study. No serious device-related adverse effects were reported. Peter Staats, MD, Chief Medical Officer for electroCore, commented, “We congratulate all the investigators and patients that supported this research into the role of nVNS as a novel, non-pharmacologic treatment for patients suffering from gastroparesis. The significant decrease in the use of rescue medications, combined with the many benefits seen in the accompanying symptoms that often plague patients with gastroparesis suggest a new and important role for nVNS.”