Aclaris Therapeutics and Pediatrix Therapeutics announced that the companies have entered into a license agreement. Under the license agreement, Aclaris has granted Pediatrix the exclusive rights to develop, manufacture and commercialize ATI-1777, Aclaris’ investigational "soft" Janus kinase, JAK, 1/3 inhibitor, for any disease, including atopic dermatitis, in Greater China. Aclaris will retain the rights to develop, manufacture and commercialize ATI-1777 in the rest of the world. Under the terms of the agreement, Aclaris will receive an upfront payment of $5 million. In addition, Aclaris is eligible to receive milestone payments of up to $91 million if certain development, regulatory and commercial objectives are achieved. Aclaris is also eligible to receive a tiered royalty ranging from a low-to-high single digit percentage of net sales of ATI-1777 by Pediatrix in Greater China. Cheng Zhang, Chief Executive Officer of Pediatrix, added, "As a "soft" JAK 1/3 inhibitor, ATI-1777 could provide patients with atopic dermatitis with a new therapeutic option which minimizes the potential for systemic toxicities. Pediatrix is excited to continue the development of ATI-1777 to bring this innovative product to patients and families in China."
Published first on TheFly
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