23andMe updates clinical immuno-oncology programs 23ME-00610 at ESMO

23andMe Holding announced that it will display three poster presentations on 23ME-00610, a first-in-class anti-CD200R1 antibody, and two on 23ME-01473, an anti-ULBP6 monoclonal antibody, at the European Society for Medical Oncology ESMO Congress 2024, taking place September 13 – September 17 in Barcelona, Spain. 23andMe will present additional preliminary clinical data, including efficacy data, for the clear-cell renal-cell carcinoma and high tumor microsatellite instability and/or high tumor mutational burden patient cohorts in the Phase 2a portion of its ongoing Phase 1/2a clinical trial evaluating 23ME-00610, as well as share further analyses on an exploratory tissue-based biomarker, CD200…The Company will present preclinical data on the 23ME-01473 program, as well as a trials in progress presentation on the Phase 1 clinical trial that began in March 2024. 23ME-01473 targets soluble ULBP6, which is released by cancer cells to promote an immunosuppressive tumor microenvironment. It is also Fc-effector enhanced to provide an additional mechanism for NK cells to induce cell death of ULBP6-expressing cancer cells.