Clinical Trial SuccessCelldex has two pivotal Phase III trials ongoing for barzolvolimab in chronic spontaneous urticaria, with a high likelihood of clinical success based on Phase II results.
Efficacy In Respiratory ConditionsThe data suggests that CDX-622 could be uniquely positioned for conditions where TSLP and mast cells may play a role, particularly in certain respiratory conditions.
Safety ProfileCDX-622 shows preferential inhibition of soluble SCF over membrane SCF, resulting in a differentiated safety profile compared to historical KIT inhibitors.